A recent Ministerial Decree, which has set forth the precise scheme of financial statements of not-for-profit entities, has introduced a relevant reference for the auditing activities to be carried out in the financial statements of not-for-profit entities. After a long debate, it is now clear that the audit opinion needs to adhere to the requirements set forth by Leg. Decree n. 39/2010 (with certain peculiarities), which also implies full application of ISA (Italia) in the audit activities.